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USMLE Vault · Step 1

Microbiology by System

Microbiology is not one subject to be conquered. It is nine finite lists, each one attached to a system you are already studying.

Studied as a single block, micro has no edges. You open the chart, scan the whole thing, and an hour disappears without a single organism actually revised — because nothing on the page told you where to stop.

Split by organ system, it has edges everywhere. Neurology is 31 organisms. Dermatology is 7. When you finish the list, the list is finished, and "done" becomes a fact rather than a feeling.

There is a second reason, and it is the better one. You already study Step 1 system by system. Doing the neurology organisms in the same week as neurology pathology means the bug and the disease get encoded together — which is exactly how the exam asks about them.

The nine system lists

Each page carries the organisms that matter for that system — whichever classes apply to it — grouped, numbered, and followed by the WRWRT method applied to one organism in full so you know what each step looks like before you repeat it.

SystemOrganismsList
Neurology31micro-cns →
Immunology28micro-immuno →
Gastrointestinal24micro-git →
Cardiovascular18micro-cvs →
Respiratory15micro-respi →
Reproductive14micro-repro →
Renal11micro-renal →
Dermatology7micro-derm →
Musculoskeletal + Dermatology13micro-msk →
Read the counts before you start. MSK and dermatology are 13 organisms together, on one page — an evening, not a week. Neurology and immunology are where the hours actually go. Plan the block around that, not around the alphabet.

All nine lists are columns of the same source chart. If you want the whole grid on one screen — searchable, filterable by the organism classes relevant to that system — that is the SystemWise Micro chart.

The method every list uses: WRWRT

Same five steps, every organism, in order. The order is the point — each step only works because of the one before it.

StepWhat it does
WWatch, 1x, no notesWalk the memory palace without stopping at every door
RRecall the story, chronologically, in your headThe only step that builds retrieval — and the one everyone skips
WWatch again — only the gaps, 1.5–1.75xYour failed recall just mapped where the time should go
RRead the Sketchy Micro PDF for those organismsConverts the image into sentences, because the exam asks in words
TTest with the Test Yourself MCQs in the First Aid Guide for those exact organismsTells you the truth about the previous four

If you want it as a full day-by-day run rather than system by system, that is the six-day Sketchy Micro protocol — same method, different container.

The T is the whole method

“Test” is not a vibe. Here is exactly where it lives.

Watch, recall, watch again, read — all four of those feel productive and prove nothing. The T is the only step that tells you the truth. And it is not you writing your own questions.

It is the First Aid Guide: all 646 pages of First Aid, decoded page by page, with 2,534 page-by-page MCQs built into them. Every page ends in Test Yourself — questions on that page, not that chapter.

What is on a single page
Focus On — what actually matters on the page
Concept Walkthrough — the teaching First Aid left out
How is this tested? — Common Confusion → Core Concept → The Trap → Your Approach
Key Takeaways
Test Yourself MCQs — the T step
Worked example
Neurology micro. The page above gives you 31 organisms for the system. Sketchy covers them; First Aid carries them on its own pages.

After you finish the WRWR on a block of organisms, open the First Aid Guide at those exact page numbers and answer the Test Yourself MCQs on each one. Same night. Not “at the weekend”.

That is how you find out whether the organisms went in, or whether you just enjoyed the video.

If you cannot answer the page, you did not learn the page. You watched a cartoon. The T is what converts twenty hours of Sketchy into marks — and skipping it is the single most common reason a student “finished micro” and still misses the organism on the form.

Want to see one before you commit? Here is exactly what one page looks like, in full.

Open the First Aid Guide — free for 3 days →
Renal is permanently free. You can run the entire T step on a full system before you decide anything.
Never touched Sketchy? Every one of these lists can be revised from First Aid alone. The list is still your list; only the source changes.

Then the drugs

Organisms without the drugs that kill them is half a block. The antimicrobials page runs the same shape — a finite group list and a method — as FWRT rather than WRWRT: the 6 antimicrobial drug groups →

It belongs to the wider pharm block, which is built on the same stratification logic: complete pharmacology in 48 hours.

How to actually use this

1
Pick the system you are studying this week. Not the shortest one, not the first one — the one your First Aid reading is already on.
2
Open that list and work down it. WRWRT on each organism. Do not go back to the chart mid-list; the chart is what made you lose the hour in the first place.
3
Stop when the list ends. Completion over perfection. The retention comes later, when UWorld puts one of these in a vignette and the visual story comes straight back.
Do this today: open the system you are currently on, count the organisms, and do WRWRT on the first one properly — all five steps, including the recall you will want to skip. One organism done properly tells you how long the whole list will take.
Where this sits in the plan.
→ Not sure a system is actually finished? When is a system actually finished.
→ The micro block as a standalone sprint: Sketchy Micro in 6 days.
→ The drugs half of the same block: Pharmacology in 48 hours.
Nine lists. One method. Finite either way.
The organism lists, the FA Guide MCQs and the Sketchy Micro PDF are all inside the Vault.
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